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About
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The core competence of BMGen is in the rapidly developing post-genomic era
scientific discipline called functional genomics. Functional genomics
explores changes and functions of genes in scope of large or even
genome-wide gene-sets. These new research approaches, which became
possible only after sequencing of the human genome was completed in 2003,
have opened completely new avenues for academic research and offer new
promising solutions for biotech and pharmaceutical companies.
Biochips are typically used to measure DNA copy number variation, mRNA or
microRNA expression alterations or DNA-protein binding interactions in a
genome-wide scale. Recombinant lentiviruses are used as carriers of a DNA
piece, which expresses a desired gene in the cells or alternatively,
produces a shRNA that switches off the expression of desired genes. This
approach can directly identify relationships between gene function and a
biological process or disease.
Functional genomics has revolutionized research and development concepts
in practically all fields of life sciences and pharmaceutical research,
generating multiple new approaches in the areas of pathway mapping, drug
discovery, toxicity profiling, lead optimization and diagnostics. BMGen
offers customers a chance to keep up with pace of rapidly evolving
technologies, maintain a state-of-art R&D portfolio and outsource part of
the research enabling customers to keep focus on their core expertise. We
provide wide range of full service analyses, in which our work starts from
the customer’s biological specimen or a gene list and we deliver customer
the wanted biological information. BMGen also invites clients to
partnerships, which encompass consultation with scientific experts,
comprehensive analysis packages and solutions including multiple
functional genomics platforms.
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