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DNA-Protein Binding Analysis

  ChIP-on-chip DNA microarrays can be used to map functional elements or binding sites for transcription factors in the genome. These platforms allow the monitoring of DNA sequences with specific protein binding to regions around e.g. the human and mouse promoters, yeast genome as well as to defined regions of the genome such as the Human ENCODE region.

Novel regions involved in transcriptional regulation can be identified using Affymetrix and Nimblegen whole genome tiling arrays. In addition, custom ChIP-on-chip arrays can be constructed for almost any organism using custom array services available in Affymetrix, Nimblegen and Agilent.